B vitamins are involved in almost every energy-producing process in the body — converting what you eat into the fuel your cells actually run on, supporting your nervous system, keeping your mood regulated, and helping your brain synthesise the neurotransmitters responsible for focus, memory, and calm. When they're in short supply, the effects show up across all of these systems at once: fatigue, brain fog, low mood, and poor stress tolerance are all common signs of B vitamin insufficiency.
The catch is that most B vitamin supplements use synthetic, non-activated forms that have to be converted by the body before they can be used. For a significant portion of the population — including those with MTHFR gene variants that are surprisingly common — this conversion is impaired, meaning a standard B complex supplement may deliver very little actual benefit regardless of the dose on the label.
Active-B Complex uses only the activated, biologically ready forms of each vitamin. B9 is provided as Quatrefolic® (5-MTHF) — clinically shown to absorb 9.7 times better than standard folic acid and able to bypass the conversion step that causes problems for MTHFR variants. B12 is methylcobalamin at a therapeutic 1000mcg dose. B6 is pyridoxal-5-phosphate (P5P) and B2 is riboflavin sodium phosphate — both activated forms that the body can use straight away. Choline is added specifically to support acetylcholine synthesis — the neurotransmitter most tied to memory, learning, and mental clarity. TGA-listed (AUST L 453869).

The activated versus non-activated distinction is the entire reason this product exists. Standard B complexes are cheap because they use synthetic forms like cyanocobalamin (B12) and folic acid (B9) that need enzymatic conversion before they become usable. Quatrefolic® skips this step entirely — it's already in the form the body uses, making it reliably absorbed regardless of your genetics.
The homocysteine angle is also worth understanding. Elevated homocysteine is an independent risk factor for cognitive decline and cardiovascular issues — and B6, B9, and B12 are the three nutrients most directly responsible for keeping it in check. Active-B Complex is formulated specifically to support healthy homocysteine metabolism, which is why it's relevant not just for daily energy and focus but for long-term brain and heart health.
Choline is included because it's frequently missing from B complex formulas and is one of the most commonly under-consumed nutrients in the population. It's a precursor to acetylcholine — meaning your brain needs it to produce the neurotransmitter responsible for memory consolidation, focus, and mental clarity. Low choline levels are directly tied to poor cognitive performance.

Per 1–2 capsule dose: Vitamin B1 (Thiamine HCl) 100mg, Vitamin B2 (Riboflavin Sodium Phosphate — activated) 50mg, Vitamin B3 (Nicotinamide) 100mg, Vitamin B5 (Calcium Pantothenate) 100mg, Vitamin B6 (Pyridoxal-5-Phosphate P5P — activated) 50mg, Biotin 2.5mg, Quatrefolic® Vitamin B9 (5-MTHF — activated) 500mcg, Methylcobalamin Vitamin B12 (activated) 1000mcg, Choline Bitartrate 200mg, Magnesium Citrate 7.72mg.
Other ingredients: Plant-derived hypromellose capsule, Silica, Magnesium Stearate (plant-based), Cellulose.
Vegan · Gluten free · Dairy free · Soy free · GMO free · TGA listed (AUST L 453869) · Australian GMP · Third-party tested
60 capsules per bottle — 30-day supply at 2 capsules/day or 60-day supply at 1 capsule/day.

Take 1–2 capsules daily with food. Do not take at night — B vitamins can be stimulating and may interfere with sleep if taken in the evening. Split your dose through the day if taking 2 capsules (e.g. one with breakfast, one with lunch).
Avoid taking near medications that suppress stomach acid, as these can reduce B12 absorption. Do not take if on warfarin therapy without medical advice. Allow a minimum of 3 months of consistent daily use to assess full benefit.

A good fit if you:

• Experience fatigue, brain fog, or low mood that isn't explained by other factors
• Know or suspect you have an MTHFR gene variant that affects B vitamin conversion
• Follow a vegan or vegetarian diet and want reliable B12 support at a therapeutic dose
• Want to support healthy homocysteine levels for long-term brain and heart health
• Are looking for a clean, high-strength B complex with no synthetic fillers
  
• Are building a Flow routine and want cognitive and energy foundations covered

• All 8 B vitamins in activated, immediately usable forms — no conversion required
• Quatrefolic® B9 — 9.7x better absorption than folic acid, bypasses MTHFR conversion issues
• Methylcobalamin B12 at 1000mcg — therapeutic dose in the most bioavailable form
• Choline 200mg — supports acetylcholine synthesis for memory and mental clarity
• Supports healthy homocysteine metabolism for long-term brain and heart health
  
• TGA-listed (AUST L 453869) · Australian GMP · No synthetic inactive forms